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Showing content with the highest reputation on 10/06/19 in all areas

  1. 16 points
    I've never understood why people need to be so committed to shitting on the quality of women's football. It's not a mystery or a secret, it's there for anyone to watch. If you like it, watch it. If you don't, don't. ?‍♂️
  2. 13 points
    I’m very uneasy at the dismantling of a group that seem to have done well over the last couple of seasons
  3. 12 points
  4. 11 points
    Home vs Everton in 2016 I left couple of minutes early to beat the traffic. Nothing much was happening. No idea why there was such a huge crowd outside
  5. 7 points
    Finally got a picture of all of the little buggers. In for their first jabs tomorrow and 4 of them off a week on Thursday
  6. 6 points
    The thing about Gove is that he understands that you can take drugs and also lead a full normal life yet chooses to destroy the lives of those who have taken drugs rather than help them. He's a twat with no integrity.
  7. 5 points
    If you think that's bad, thats my dad getting pushed by Ian Walker
  8. 5 points
    We've lost people in these departments from pretty much the moment we got promoted... Wrigglesworth left for Arsenal Mackenzie left for Spurs Walsh left for Everton It was a disaster when they all left on here, but we continued to find good players. In fact last summer was one of our best. It's not just about individuals, but an overall process of identification. If we have an ideology in place from the days of Walsh and we continue to follow it and it's processes, there is no reason as to why we can't keep identify good targets no matter who moves on. Much of the scouting is technical, which means looking at sets of data. If we have markers that we look for, then it doesn't matter who is crunching the numbers. That sets things in motion and will then narrow down players to be watched in person.
  9. 5 points
    It's very obvious what the topic is so why view it if it bothers you so much and why post in it helping to keep it on the front page?
  10. 5 points
    How thoroughly dismaying the reaction to the Gove drugs story is. All we are hearing from our politicians - including the hypocrite Gove himself - is the familiar rhetoric of 'drugs are bad' and 'think of the hidden victims like the child traffickers of the County Lines set-up' and 'all the money going to gangs' - all of which is a direct result of prohibition. Meanwhile, the most socially destructive drug of all fills whole aisles of the supermarkets to be bought alongside the weekly shop. When is this backward country going to have a grown-up discussion on legalisation?
  11. 5 points
    Science is finally catching up with what some of us have always known: 'They broke my mental shackles': could magic mushrooms be the answer to depression? New trials have shown the drug psilocybin to be highly effective in treating depression, with Oakland the latest US city to in effect decriminalise it last week. Some researchers say it could become ‘indefensible’ to ignore the evidence – but how would it work as a reliable treatment? ying on a bed in London’s Hammersmith hospital ingesting capsules of psilocybin, the active ingredient of magic mushrooms, Michael had little idea what would happen next. The 56-year-old part-time website developer from County Durham in northern England had battled depression for 30 years and had tried talking therapies and many types of antidepressant with no success. His mother’s death from cancer, followed by a friend’s suicide, had left him at one of his lowest points yet. Searching online to see if mushrooms sprouting in his yard were the hallucinogenic variety, he had come across a pioneering medical trial at Imperial College London. Listening to music and surrounded by candles and flowers in the decorated clinical room, Michael anxiously waited for the drug to kick in. After 50 minutes, he saw bright lights leading into the distance and embarked on a five-hour journey into his own mind, where he would re-live a range of childhood memories and confront his grief. For the next three months, his depressive symptoms waned. He felt upbeat and accepting, enjoying pastimes he had come to feel apathetic about, such as walking through the Yorkshire countryside and taking photographs of nature. “I became a different person,” says Michael. “I couldn’t wait to get dressed, get into the outside world, see people. I was supremely confident – more like I was when I was younger, before the depression started and got to its worst.” The trial, finished in 2016, was the first modern study to target treatment-resistant depression with psilocybin, a psychedelic drug naturally occurring in around 200 species of mushroom. To varying degrees, Michael and all 18 other participants saw their symptoms reduce a week after two treatments, including a high, 25mg dose. Five weeks later, nine out of 19 patients found that their depression was still significantly reduced (by 50% or more) – results that largely held steady for three months. They had suffered from depression for an average of 18 years and all had tried other treatments. In January this year, the trial launched its second stage: an ambitious effort to test psilocybin on a larger group and with more scientific rigour (including a control group, which Michael’s study lacked), comparing the drug’s performance with escitalopram, a common antidepressant. The team has now treated about a third of the 60 patients and say that early results are promising for psilocybin. Imperial’s current work is among a string of new studies that a group of professors, campaigners and investors hope will lead to psilocybin’s medical approval as a transformative treatment. Others soon to begin include an 80-person study run by Usona Institute, a Wisconsin-based medical non-profit, and a trial at King’s College London, as well as a 216-person trial that is already under way around the US, Europe and Canada, managed by the London-based life sciences company Compass Pathways. Robin Carhart-Harris, head of Imperial’s Centre for Psychedelic Research and a Compass scientific adviser, believes psilocybin could be a licensed medicine within five years, or potentially even sooner. “By about that point,” he says, “it would be like an irresistible force, and indefensible to ignore the weight of the evidence.” Psilocybin mushrooms have been part of religious rituals for thousands of years. The Aztecs of Mexico referred to the mushroom as teonanácatl, or “God’s flesh”, in homage to its believed sacred power. In 1957, Albert Hoffman, a Swiss chemist working for the pharmaceutical company Sandoz, isolated psilocybin from the mushroom. Fifteen years earlier, he had accidentally ingested LSD, left work feeling dizzy, and experienced its psychedelic effects when he got home. During the 1960s, Sandoz sold psilocybin and LSD for research in medical trials, but the substances were soon outlawed after they became associated with the 60s counterculture. Psilocybin remains in the most restricted category today under the UN Convention on Psychotropic Substances, the US 1970 Controlled Substances Act and the 1971 UK Misuse of Drugs Act, among others. David Nutt, a professor of neuropsychoparmacology at Imperial, who is overseeing the current trials, disputes the evidence for this, saying that heavily restricting the drug (and other psychedelics) has hindered research and propelled “lies” about its risks and medical potential. For him, the decision is “one of the most atrocious examples of the censorship of science and medicine in the history of the world”. If successful, the new wave of research may continue to change psilocybin’s reputation after decades of prohibition. Carhart-Harris believes the drug offers a better and more comprehensive treatment than current antidepressants, and that it could well be a powerful new therapy for a host of other mental illnesses, including anxiety and food disorders. A 2016 Johns Hopkins University study of 51 patients with life-threatening cancer showed high doses of psilocybin significantly reduced end-of-life depression and anxiety for six months in 80% of cases, and helped patients accept death; a New York University study that year showed similar results. Current trials are looking further at psilocybin’s potential for reducing smoking addiction and alcohol dependency, after initial pilots yielded powerful results. (Johns Hopkins researchers showed in a small study, for example, that 80% of heavy smokers had not smoked for a least a week, six months after psilocybin treatment.) Carhart-Harris thinks part of the reason the drug has been effective in treating depression in trials so far is that it can help people see their lives more clearly. When watching patients tripping, he often feels as if they see a truer version of reality than the sober therapists guiding them: “It is almost like being in the presence of someone particularly wise, in terms of what comes out of their mouth.” It is unclear how much of the depression alleviation comes from the psychiatric support surrounding the treatment. Either way, several patients have sourced top-ups independently since the first trial, as their depression has returned. Much about the neuroscience of psychedelics remains unknown, but fMRI scans of patients’ brains after taking psilocybin showed reduced blood flow and resting activity in the amygdala, which is often overactive in depression and anxiety. They also show looser connections between brain networks, which then reintegrate in what the Imperial team suggests is part of the brain “resetting” itself on psilocybin. This may explain why the drug drives some patients to rethink entrenched beliefs and break compulsive thought patterns and behaviours. Imperial researchers believe that psilocybin operates differently from most current treatments. If common antidepressants dull emotions to help people cope, they theorise, psilocybin works on our serotonin system to heighten emotional responses and encourage people to actively confront their depression, which can prompt enduring shifts in mind-set. For 48-year-old university design technician Kirk Rutter, this is why psilocybin seems to work – and why he hopes it will become medically available. He sees the drug not as a silver bullet but as a medicine that shows patients deep truths and requires them to apply teachings of this kind. Some other treatments, such as cognitive behavioural therapy, also seek to reshape thinking patterns, often in conjunction with antidepressants, but for many the current options fail to work. More than 300 million people suffer from depression globally, according to the World Health Organization, but researchers say that many of the most serious cases do not respond to antidepressants. Rutter was in this group, having tried counselling and two prescription medicines in the five years before the Imperial trial, as his depression worsened following his mother’s death. After psilocybin, he began to break cycles of catastrophic thinking and had the confidence to make profound life changes, such as selling his house and moving away from abusive neighbours, reorganising his finances and travelling for enjoyment after years of not leaving the country. He says of psilocybin: “It removes any barriers and allows you to process what you need to in an almost seductive way. You are inevitably and irresistibly drawn into it.” One week after the treatment, he noticed a feeling of optimism come back to his life. “Hell,” he thought, “I haven’t had this for a long time.” Even psilocybin’s fiercest proponents agree that it will take more evidence of its effectiveness on larger groups in controlled settings, and investigation into potential adverse effects, before it can be unleashed as a medicine. Current trials exclude people with a family history of psychosis for fear that the drug could trigger latent schizophrenia. And there are questions about psilocybin’s impact. Some patients say they hardly experienced the psychedelic effects, while others such as Michael had strong reactions to lower doses but less to higher ones. James Rucker, who worked on the first Imperial study and now directs psilocybin trials at King’s College London, remains agnostic about the drug as a reliable treatment. “It’s an illusion that we know so much about psilocybin,” says Ekaterina Malievskaia, co-founder of Compass, which hopes to sell the drug as part of an approved treatment. “We really don’t. We know it can cause profound personal experiences; it can also cause all sorts of complications.” But Malievskaia hopes that the Compass trials will provide the evidence needed to get the drug medically approved for treatment-resistant depression. She founded the company with her husband, George Goldsmith, three years ago, after her son’s severe depression and OCD got progressively worse while he was being treated with traditional antidepressants in a top US hospital. He later recovered with the help of psilocybin therapy, and the company says it has now attracted around £28m in funding, including from the venture capitalist Peter Thiel, and has applied to patent a process to make psilocybin at scale. Some former Compass associates fear the company seeks to monopolise the psilocybin market and control medical access, criticisms that were aired last year by the US business website Quartz, although Malievskaia denies this. There are already signs that authorities may be beginning to shift. In October, US regulators gave Compass’s treatment breakthrough therapy status, a designation given to new medicines that might improve treatments for serious conditions, which means authorities will expedite their review of evidence. That decision was followed this May with Denver’s vote to in effect decriminalise magic mushrooms, making it the first US city to do so, followed last week by a similar measure for several psychedelic plants in Oakland, California. Activists are pushing for a state-wide vote in Oregon next year on whether to legalise psilocybin for medical use. Meanwhile, Compass hopes to request marketing authorisation for the drug within three years, if its trials are successful. It is proceeding slowly, though, having treated around six people since trials began in January, and Malievskaia says the process could take a decade until approval. She aims to accelerate progress, with new treatment sites recently opened at Columbia University, as well as in New Orleans and the Netherlands, among others. Licensing is not the only obstacle to the drug becoming a common medicine. Taken over multiple hours in clinical settings with expert guides, psilocybin therapy does not come cheap. The new Imperial treatments cost more than £2,000 each, including doctors and therapists, and many patients could need multiple treatments each year for continued benefits. Malievskaia would not comment on how much Compass would plan to charge, but says she wants to maximise how many people can access the drug. Carhart-Harris says psilocybin therapy would be significantly more expensive than antidepressants and potentially more than counselling. “There is a cold reality to why selective serotonin reuptake inhibitors [antidepressants] dominate mental healthcare and that is that they are cheap,” he says. The scientific, legal and commercial challenges may take years to be settled. But for many of the patients who have already been treated, and for some of the therapists guiding them, there is little doubt: it is only a matter of time before psilocybin and similar psychedelics reshape how we treat suffering – and understand our minds. Forty-year-old operations manager Melissa Elwin is among them. After an unpleasant first treatment, in which she felt trapped, during her second psychedelic trip inside Hammersmith Hospital, she felt as though she had left her body and was seeing her problems objectively. Psilocybin helped her confront her depression, fuelled by a difficult relationship and fraught breakup, and anxiety she had had since childhood. Under the drug, she started to find a resilience that has since helped her face her father’s death from dementia and a protracted legal battle with her ex-partner. Her descriptions of the trip are similar to the awe and unity Hoffman at times experienced on psychedelics while testing them: he saw in them a powerful ability to put our self and troubles in perspective. “I was literally everywhere [during the psilocybin trip],” says Elwin. “In the most amazing nature scenes, like the orb of light twinkling through trees, in the ocean, in waterfalls. I had no recollection of time and I just wanted it to last for ever. For so long, I felt my depression was part of me, there was nothing I could do to change it. The antidepressants only made me feel drowsy and stopped me caring about things. This made me completely break my mental shackles. I returned to work [after being unemployed] and I was euphoric. I felt: I can do this, I can change my situation.”
  12. 4 points
    Mark King of Level 42, now he is quality....
  13. 4 points
  14. 4 points
    Why did you wear a Leicester scarf?
  15. 4 points
    Do you sell what you're on or is it personal use only? Genuinely curious.
  16. 4 points
    All those leaver £50-80k earners in the Midlands and North East will be delighted.
  17. 4 points
    Just reminded me of Alan Brazil ranting about Bellerin's diet
  18. 4 points
    Iborra was fine compared to the other two. Did a good enough job and we sold for pretty much the amount we bought him for.
  19. 4 points
    Let Bielsa have him for a season at Leeds, could be phenomenal or a complete disaster.
  20. 4 points
    I always thought he was weirdly shit in the air for such a giant. It was even more weird that he seemed better as a wide forward given his attributes. He frustrated me, but I kind of still liked him. The Brian Little era is also one that, for me, was one that re-booted the club and put us on a path towards better things, which ultimately culminated in the two League Cup wins under O’Neill.
  21. 3 points
    A bit of love for Sinatra here which is understandable but if he's in then I'll add Dean Martin. He's got such a swagger in his voice, love it. Females I'll add Lauryrn Hill and Martha Reeves.
  22. 3 points
    Male: Sam Cooke, Elvis Presley, Johnny Cash, Otis Redding, Freddie Mercury, John Lennon, Frank Sinatra, Frankie Valli, Carl Wilson, Joey Ramone Female: Dusty Springfield, Aretha Franklin, Ronnie Spector, Janis Joplin, Etta James, Nina Simone, Ella Fitzgerald, Billie Holliday
  23. 3 points
    Really sorry that you feel like your life is falling apart. I wouldn't like to ask about the specific problems of someone I don't know but I urge you to try everything you can to remain positive. Things can quite often change very quickly when something unexpected happens to make things better. A lot of people will have had this sort of experience after some very bad times. Hopefully something will somehow happen to lift you. If you can keep hold of your ST rather than giving it up, it may help to take your mind off the bad things and bring you some happiness while supporting your team.
  24. 3 points
    So as some of us mentioned, the sharp dart to the right as Vettel rejoined the track was what caused the officials to make their decision. Not to mention it appears Vettel checked his mirrors, probably (or surely?!) saw Hamilton and chose to let his car still go towards the right of the track as he rejoined...
  25. 3 points
    Hunt master filmed throwing fox cubs to a pack of hounds: https://www.theguardian.com/uk-news/2019/jun/10/huntsman-found-guilty-of-animal-cruelty-after-activists-secret-filming
  26. 3 points
    Have to mention The Planets with Brian Cox. Magical.
  27. 3 points
    No i don't think so, as far as i was aware it had to be a body-part that was acceptable to score, which triggers you being offside.
  28. 3 points
    All the Tory leadership contenders are proper shit.
  29. 3 points
    Whilst I agree with some of the points you make, I'm not sure if Iheanacho does have the talent. I would imagine most average strikers would score goal in the Manchester City side of recent years. Pep obviously couldn't see it in him, Puel improved all our younger players, Rodgers the same. All are known to be excellent in improving young players, and all have done, with the exception of Iheanacho. The comments by his National Manager sum him up, and even after being given another chance his manager was still highly critical of his attitude. He has shown very little to me that he has the talent to succeed. He also has shown absolutely no desire to succeed. To have paid £25 MILLION for him, plus his obscene wages, he is stealing a living as a P/L footballer. The quicker we get shot of him the better.
  30. 3 points
    In athletics, the world records for women are frequently considerably 'worse' than the national record for American high school boys. Yet those achievements are - rightfully so - still given the credit they deserve and those women are lauded as being at the pinnacle of sport. For some reason, that admiration seems to go completely out of the window when it comes to football. Yes the standard across the board is lower, but this is still the top level of the sport and slandering it by comparing apples to oranges is completely unnecessary. If you don't like it don't watch it, but no need to attempt to degrade it at every opportunity.
  31. 3 points
    Dismantling, or does he just like the thought of living in France. This place needs a panic room.
  32. 3 points
    The overhaul is happening whether it's our own doing or out of our control. Head of the Academy gone. Head of Recruitment gone. Head of Scouting gone. Let's hope the replacements are equally as good, if not better. ?
  33. 3 points
    so what? Pointless poll (wherever it is - since you don't link it) which serves only to feed the narrative of belittling the women's game. Participation by girls in football is on the up and has been for years. This is a good thing. There is no need to compare the two since they won't be playing against each other.
  34. 3 points
    Great player, won Man City the league this year.
  35. 3 points
  36. 3 points
    Had our presentation awards evening for the U10's this evening. I did a little speech about the season and each player which went down well with the kids and the parents I think. Then at the end I was presented with a card that everyone had signed, an engraved pen and coffee mug and a Nike coaches top with my initials on it. Was really touching and felt quite emotional actually. All the aggravation of the season was worth while in the end
  37. 3 points
    Right man, right place, right time. The planets aligned for the most glorious of seasons.
  38. 2 points
    Our 90's season reviews had some excellent intro music. Especially 1993/94 and 1997/98.
  39. 2 points
    Yeah like all of Meadows work it's really dark in places and uncomfortable viewing but superbly real. The dialogue is brilliant
  40. 2 points
  41. 2 points
    Yes but like in any other business, if you have a team with an good track record and it slowly dismantles itself (intentionally or otherwise) and the person coming in has a questionable background, you'd feel unconformable. It's the same here.
  42. 2 points
    Got lobbed out of Blackpool for ‘persistent standing’.
  43. 2 points
    If these bastards don't hang then there's no justice in this world: https://www.theguardian.com/world/2019/jun/10/india-six-guilty-of-child-and-that-outraged-nation
  44. 2 points
    He was "Head of Technical Scouting and Senior Scouting Coordinator".
  45. 2 points
    The fact this happened 3 months ago isn't really relevant, the potential problems still exist whereby we have lost our Head of Recruitment who had been lined up by Bordeaux several months ago and our head of scouting obviously agreed to go with him. In more recent weeks, our Head of the Academy has decided to go to West Ham. This could all be great, we are an ambitious club and if the replacements are a higher calibre then it's positive. If they've all jumped ship though and we get the replacements wrong then it's a serious issue.
  46. 2 points
    Yep that's my point, even the dodgier signings have been OK. Even Silva might turn out to be useful if we bag Tielemans. Nacho hasn't worked out but on paper signing a very promising striker who had proven experience and goals at Premier League level looked like a great move. There isn't a single club in the world that has a 100% hit rate success with transfers - even Man City under Pep and Liverpool under Klopp have had some duds. But in 16/17 some of our signings like Musa, Kapustka and Hernandez were very poor and there was a reason why the football world at large was very surprised with the players that we brought in. Somehow we got some money back from those players, but we are also still hampered with Slimani who still had a decent impact but was in no shape or form a 30m player and one that is costing us a lot of money in wages still that we are unlikely to ever recoup. For clubs in the "best of the rest" mini-league, transfers are so crucial. Throw it all away on some poor ones and you can tumble down the table and struggle. Sign some gems that went under the radar and you might get top 6 or 7 occasionally. That's why we are right be slightly worried with the new head of recruitment and that some of our proven backroom staff are off on their way!
  47. 2 points
    I echo your sentiments. Macia did well I thought to adjust for the disastrous 16/17 window with some very reasonable and well thought out signings. Even the ones that didn't make the grade such as Nacho, Silva and Iborra were on paper pretty decent.
  48. 2 points
    Derby half marathon today same as Liverpool for me went off too fast and paid heavily later 1.48.15 in the end
  49. 2 points
    Shane Meadows has a very different way of directing, its more akin to watching a documentary rather than watching people acting, very compelling, like This is England, a tough and at times a difficult watch, but quality TV.
  50. 2 points
    My cousin (the same age as me (mid-20s)) got married last week, has a house, dogs etc. My friends are all buying houses with their partners. Yet I have no commitments, no partner, no car, I'm trouping through a masters degree with a 12 hour per week job to keep my bank account ticking over and yet while rarely I get jealous, I'm much happier following my path in life, doing the things I want to do when I want to do them and not conforming to what's seen as the norm. Embrace being an uncle, it'll teach you a lot about life. I think 'sorting your life out' is an impossible task for anyone and is doomed to fail, you just need to be easier on yourself, que sera que sera, take everyday as it comes!!
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