Stephen Carr, Celestine Babayaro, Damien Duff, skipper Scott Parker and strikers Obafemi Martins and Shola Ameobi were not among the 23-man party which left for Sicily on Wednesday.
Keeper Shay Given has made the trip to Palermo, but will not feature as he continues his recovery from abdominal surgery.
With Giuseppe Rossi ineligible, Roeder seems set to hand a chance to Albert Luque to kick-start his Newcastle career.