I get that it would be difficult to construct this in any other way, but the impact on the team will obviously depend on how likely that player would have been to start if fully fit.
Man City have probably seen the biggest impact of this, losing Rodri and his back up for a while has seen them tank. Similarly us missing Hermansen, Fatawu, Winks, and Ndidi is obviously worse than if it were Ward, BDCR, Skipp, and Hamza.